Transposon-associated polymorphisms of stress-responsive gene promoters in selected accessions of Arabidopsis thaliana

Acta Biochim Pol. 2018;65(3):391-396. doi: 10.18388/abp.2017_1590. Epub 2018 Aug 27.

Abstract

Genetic diversity caused by transposable element movement can play an important role in plant adaptation to local environments. Regarding genes, transposon-induced alleles were mostly related to gene bodies and a few of them to promoter regions. In this study, promoter regions of 9 stress-related genes were searched for transposable element insertions in 12 natural accessions of Arabidopsis thaliana. The promoter screening was performed via PCR amplification with primers designed to flank transposable element insertions in the promoter regions of the reference accession Col-0. Transposable element-associated insertion/deletion (indel) polymorphisms were identified in 7 of the 12 promoter loci across studied accessions that can be developed further as molecular markers. The transposable element absence in the promoter regions of orthologous genes in A. lyrata indicated that the insertion of these transposable elements in A. thaliana lineage had occurred after its divergence from A. lyrata. Sequence analysis of the promoter regions of CML41 (Calmodulin-like protein 41) and CHAP (chaperone protein dnaJ-related) confirmed the indel polymorphic sites in four accessions - Col-0, Wassilewskija, Shahdara, and Pirin. The observed indel polymorphism of the CHAP promoter region was associated with specific gene expression profiles in the different accessions grown at a normal and elevated temperature in a plant growth chamber. The collected data can be a starting point for gene expression profiling studies under conditions resembling the natural habitats of accessions.

Keywords: Arabidopsis; natural accessions; promoters; transposable elements.

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis / physiology
  • Arabidopsis Proteins / genetics
  • Calcium-Binding Proteins / genetics
  • DNA Transposable Elements*
  • Gene Expression Profiling
  • Genes, Plant*
  • Genetic Markers
  • INDEL Mutation
  • Molecular Chaperones / genetics
  • Polymerase Chain Reaction
  • Polymorphism, Genetic*
  • Promoter Regions, Genetic*
  • RNA, Messenger / genetics
  • Stress, Physiological / genetics*

Substances

  • Arabidopsis Proteins
  • CML41 protein, Arabidopsis
  • Calcium-Binding Proteins
  • DNA Transposable Elements
  • Genetic Markers
  • Molecular Chaperones
  • RNA, Messenger