Rhodium(III)-Catalyzed Oxidative Annulation of Acrylic Acid with Alkynes: An Easy Approach to the Synthesis of α-Pyrones

Chem Asian J. 2018 Nov 2;13(21):3281-3284. doi: 10.1002/asia.201801190. Epub 2018 Oct 2.

Abstract

A highly efficient rhodium(III)-catalyzed direct oxidative annulation of acrylic acid with alkynes to form α-pyrones was developed. Various substituted acrylic acids were compatible in this transformation, affording the corresponding products in moderate to excellent yields under mild conditions.

Keywords: C−H activation; acrylic acid; oxidative annulation; rhodium; α-pyrone.