Topical carbocysteine: A new option for the treatment of ichthyosis

Pediatr Dermatol. 2018 Nov;35(6):e357-e359. doi: 10.1111/pde.13638. Epub 2018 Aug 28.

Abstract

N-acetylcysteine in combination with urea is effective for the treatment of congenital ichthyosis. Although it is well tolerated, its foul smell may compromise treatment adherence. Carbocysteine is a similar molecule without that bad odor. Thus, we have tried a new formula with carbocysteine for the treatment of 4 patients with ichthyosis, with positive results.

Keywords: ichtyhosis; treatment.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Anti-Infective Agents, Local / administration & dosage*
  • Carbocysteine / administration & dosage*
  • Child
  • Child, Preschool
  • Drug Combinations
  • Humans
  • Ichthyosis / drug therapy*
  • Male
  • Middle Aged
  • Urea / administration & dosage

Substances

  • Anti-Infective Agents, Local
  • Drug Combinations
  • Carbocysteine
  • Urea