In this work, a novel active-inactive material interdigitated aggregates (AIMIAs) structure was constructed by self-assembled wormlike micelles (WLMs) and one-dimensional cellulose nanofiber (CNF). The rheological behaviors and microstructures of the AIMIA systems with different CNF concentrations were investigated by rheometer, cryogenic transmission electron microscopy, and environmental scanning electron microscope. Some key parameters, including zero-shear viscosity (η0), relaxing time (τR), and contour length ( L), were calculated to analyze the changes in the properties of different systems. Meanwhile, a proper mechanism describing the interaction between CNF and WLMs was proposed. Through this work, we expect to deepen the understanding of the AIMIAs structure and widen its application.