Contemporary prostate cancer radiation therapy in the United States: Patterns of care and compliance with quality measures

Pract Radiat Oncol. 2018 Sep-Oct;8(5):307-316. doi: 10.1016/j.prro.2018.04.009.

Abstract

Purpose: Quality measures represent the standards of appropriate treatment agreed upon by experts in the field and often supported by data. The extent to which providers in the community adhere to quality measures in radiation therapy (RT) is unknown.

Methods and materials: The Comparative Effectiveness Analysis of Surgery and Radiation study enrolled men with clinically localized prostate cancer in 2011 and 2012. Patients completed surveys and medical records were reviewed. Patients were risk-stratified according to D'Amico classification criteria. Patterns of care and compliance with 8 quality measures as endorsed by national consortia as of 2011 were assessed.

Results: Overall, 926 men underwent definitive RT (69% external beam radiation therapy [EBRT]), 17% brachytherapy (BT), and 14% combined EBRT and BT with considerable variation in radiation techniques across risk groups. Most men who received EBRT had dose-escalated EBRT (>75 Gy; 93%) delivered with conventional fractionation (<2 Gy; 95%), intensity modulated RT (76%), and image guided RT (85%). Most men treated with BT received I125 (77%). Overall, 73% of the men received EBRT that was compliant with the quality measures (dose-escalation, image-guidance, appropriate use of androgen deprivation therapy, and appropriate treatment target) but only 60% of men received BT that was compliant with quality measures (postimplant dosimetry and appropriate dose). African-American men (64%) and other minorities (62%) were less likely than white men (77%) to receive EBRT that was compliant with quality measures.

Conclusions: Most men who received RT for localized prostate cancer were treated with an appropriately high dose and received image guidance and intensity modulated RT. However, compliance with some nationally recognized quality measures was relatively low and varied by race. There are significant opportunities to improve the delivery of RT and especially for men of a minority race.

MeSH terms

  • Aged
  • Brachytherapy / methods
  • Brachytherapy / standards
  • Brachytherapy / statistics & numerical data
  • Dose Fractionation, Radiation
  • Guideline Adherence / statistics & numerical data*
  • Health Care Surveys / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians'
  • Prostate / diagnostic imaging
  • Prostate / pathology
  • Prostate / radiation effects
  • Prostatic Neoplasms / diagnostic imaging
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / radiotherapy*
  • Quality Control*
  • Radiation Oncology / organization & administration*
  • Radiation Oncology / statistics & numerical data
  • Radiotherapy Dosage
  • Radiotherapy, Image-Guided / methods
  • Radiotherapy, Image-Guided / standards
  • Radiotherapy, Image-Guided / statistics & numerical data
  • Radiotherapy, Intensity-Modulated / methods
  • Radiotherapy, Intensity-Modulated / standards
  • Radiotherapy, Intensity-Modulated / statistics & numerical data
  • United States