Delayed perforation after endoscopic submucosal dissection for mucosal colon cancer: A conservatively treated case

Fukushima J Med Sci. 2018 Dec 8;64(3):157-162. doi: 10.5387/fms.2018-04. Epub 2018 Sep 8.

Abstract

A 66-year-old man was diagnosed from colonoscopy as having a 40-mm elevated tumor in the cecum. With a preoperative diagnosis of intramucosal carcinoma, endoscopic submucosal dissection (ESD) was performed. The tumor was resected en bloc, yielding a specimen with a 66-mm diameter. No perforation was detected during the operation.Although neither abdominal pain nor fever was observed immediately after ESD, abdominal pain developed on the following day. Two days after ESD, the abdominal pain ceased. The patient was managed conservatively with fasting and intravenous antibiotic treatment. Four days after ESD, abdominal X-ray revealed marked gas retention. Computed tomography revealed pneumoperitoneum and a pelvic abscess, leading to a diagnosis of delayed perforation after colonic ESD and paralytic intestinal obstruction. A decompression tube was then inserted transnasally into the small intestine. Because a gradual decrease occurred in intestinal gas, the decompression tube was removed. Oral ingestion was resumed 13 days post-ESD.Delayed perforation after colonic ESD often requires emergency surgery. The present case was managed conservatively, despite paralytic intestinal obstruction. This approach is rarely employed for this condition and is therefore worth reporting.

Keywords: colon cancer; complication; endoscopic resection; endoscopic submucosal dissection; perforation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cecal Neoplasms / diagnosis
  • Cecal Neoplasms / surgery
  • Colonic Neoplasms / diagnosis
  • Colonic Neoplasms / surgery*
  • Conservative Treatment
  • Endoscopic Mucosal Resection / adverse effects*
  • Humans
  • Intestinal Perforation / diagnosis
  • Intestinal Perforation / etiology*
  • Intestinal Perforation / therapy
  • Male
  • Time Factors