Abstract
This study describes a successful, targeted intervention in central venous access device routine care to decrease central line-associated bloodstream infection. Taurolidine-citrate locks significantly reduced the rate of central line-associated bloodstream infection, particularly Gram-negative organisms without adverse events.
MeSH terms
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Adolescent
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Anti-Infective Agents, Local / pharmacology*
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Bacteremia / prevention & control*
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Catheter-Related Infections / microbiology
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Catheter-Related Infections / prevention & control*
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Catheterization, Central Venous / adverse effects
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Catheterization, Central Venous / instrumentation
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Catheters, Indwelling / adverse effects*
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Central Venous Catheters / adverse effects*
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Child
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Child, Preschool
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Citric Acid / pharmacology
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Cross Infection / microbiology
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Cross Infection / prevention & control
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Female
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Gram-Negative Bacteria / drug effects
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Humans
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Infant
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Male
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Taurine / analogs & derivatives*
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Taurine / pharmacology
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Thiadiazines / pharmacology*
Substances
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Anti-Infective Agents, Local
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Thiadiazines
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Taurine
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Citric Acid
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taurolidine