Infections due to antibiotic-resistant bacteria in children are on the rise worldwide. Treating these infections is a challenge for pediatric caregivers. In this arms race, the armamentarium of antibiotics is quickly being depleted. This article reviews the problems facing clinicians caring for children with resistant bacterial infections, examines some of the newer antibiotics, and discusses other methods for pediatric caregivers to combat these infections. Only through an informed and concerted effort will we be able to address this growing problem in children. [Pediatr Ann. 2018;47(9):e354-e358.].
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