Significant joint-destructive association of HLA-DRB1*04:05 independent of DAS28 in rheumatoid arthritis

Ann Rheum Dis. 2019 Feb;78(2):284-286. doi: 10.1136/annrheumdis-2018-214022. Epub 2018 Sep 19.

¹ Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
² Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan.
³ Department of the Control for Rheumatic Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan.
⁴ Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
⁵ Department of Health Information Management, Kurashiki Sweet Hospital, Kurashiki, Japan.
⁶ Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan [email protected].
⁷ Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
⁸ Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan.
⁹ The Department of Applied Genetics, The School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.

No abstract available

Keywords: HLA; SHS; genetics; rheumatoid arthritis; time-averaged DAS28.

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