Antimicrobial Susceptibility of Neisseria gonorrhoeae Isolates in Yaoundé, Cameroon From 2009 to 2014

Sex Transm Dis. 2018 Dec;45(12):e101-e103. doi: 10.1097/OLQ.0000000000000915.

Abstract

We investigated the antimicrobial resistance in gonococci 2009 to 2014 in Yaoundé, Cameroon, and recommend revisions of the Cameroonian treatment guideline. We observed a high resistance to ciprofloxacin (17.6%) but no ceftriaxone resistance. Ceftriaxone should replace ciprofloxacin as the recommended first-line treatment for urethral/vaginal discharge. Enhanced resistance surveillance in Africa is essential.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology*
  • Azithromycin / pharmacology
  • Cameroon
  • Ciprofloxacin / pharmacology
  • Drug Resistance, Multiple, Bacterial*
  • Female
  • Gonorrhea / microbiology
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Neisseria gonorrhoeae / drug effects*
  • Neisseria gonorrhoeae / isolation & purification
  • Practice Guidelines as Topic
  • Sentinel Surveillance
  • Vagina / microbiology

Substances

  • Anti-Bacterial Agents
  • Ciprofloxacin
  • Azithromycin