Dataset of plasma and aqueous humor cytokine profiles in patients with exudative age related macular degeneration and polypoidal choroidal vasculopathy

Praveen Kumar Balne; Rupesh Agrawal; Veonice Bijin Au; Bernett Lee; Arkasubhra Ghosh; Swaminathan Sethu; Mukesh Agrawal; Raja Narayanan; John Connolly

doi:10.1016/j.dib.2018.05.085

Dataset of plasma and aqueous humor cytokine profiles in patients with exudative age related macular degeneration and polypoidal choroidal vasculopathy

Data Brief. 2018 May 24:19:1570-1573. doi: 10.1016/j.dib.2018.05.085. eCollection 2018 Aug.

Authors

Praveen Kumar Balne^{1

2}, Rupesh Agrawal^{1

2}, Veonice Bijin Au³, Bernett Lee⁴, Arkasubhra Ghosh⁵, Swaminathan Sethu⁵, Mukesh Agrawal⁶, Raja Narayanan⁷, John Connolly³

Affiliations

¹ National Healthcare Group Eye Institute, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.
² Singapore Eye Research Institute, Singapore 169856, Singapore.
³ Institute of Molecular and Cell Biology, Singapore 138673, Singapore.
⁴ Singapore Immunology Network, Singapore 138648, Singapore.
⁵ GROW Research Laboratory, Narayana Nethralaya Foundation, 560099, India.
⁶ Vimta Labs Limited, Hyderabad, Telangana 500051, India.
⁷ L. V. Prasad Eye Institute, Hyderabad, Telangana 500034, India.

Abstract

In this report the data was obtained from a prospective case-control study with a sample size of sixteen patients with exudative age related macular degeneration (AMD) due to choroidal neovascularization (CNV) and eighteen patients with polypoidal choroidal vasculopathy (PCV) and fifty controls (cataract patients without any other ocular diseases). Luminex bead based multiplex assay with a panel of 41 analytes was used to study the cytokine levels in plasma and aqueous humor.

Keywords: Aqueous humor; Choroidal neovascularization, Polypoidal choroidal vasculopathy; Cytokine profiles; Exudative age related macular degeneration; Plasma.