Nothing to Be Sniffed At: Anosmin1 Tunes Fgf Diffusivity

Hannah M Olson; Alex V Nechiporuk

doi:10.1016/j.devcel.2018.09.004

Nothing to Be Sniffed At: Anosmin1 Tunes Fgf Diffusivity

Dev Cell. 2018 Sep 24;46(6):674-676. doi: 10.1016/j.devcel.2018.09.004.

Authors

Hannah M Olson¹, Alex V Nechiporuk²

Affiliations

¹ Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, The Knight Cancer Institute, Portland, OR 97219, USA; Neuroscience Graduate Program, Oregon Health & Science University, Portland, OR, USA.
² Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, The Knight Cancer Institute, Portland, OR 97219, USA. Electronic address: [email protected].

PMID: 30253166
DOI: 10.1016/j.devcel.2018.09.004

Abstract

The extracellular matrix plays both positive and negative roles in growth factor diffusion, a process critical for organ formation. In this issue of Developmental Cell, Wang et al. (2018) identify the extracellular matrix protein Anosmin1 as a key regulator of Fgf diffusion during sensory organ formation in zebrafish.

Publication types

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MeSH terms

Animals
Fibroblast Growth Factors
Zebrafish Proteins*
Zebrafish*

Substances

Zebrafish Proteins
Fibroblast Growth Factors