B cells drive auto-T cells to the brain

Sci Immunol. 2018 Oct 5;3(28):eaav4512. doi: 10.1126/sciimmunol.aav4512.

Authors

Jenna L Pappalardo¹, Kevin C O'Connor¹

Affiliation

¹ Departments of Neurology and Immunobiology, Yale University School of Medicine, New Haven, CT 06520 USA. Email: [email protected] and [email protected].

PMID: 30291134
DOI: 10.1126/sciimmunol.aav4512

Abstract

Self-reactive T cells that traffic to the brain tissue of patients with multiple sclerosis are driven by antigen-experienced B cells.

Copyright © 2018, American Association for the Advancement of Science.