Selected Case From the Arkadi M. Rywlin International Pathology Slide Seminar: Atypical Thymoma With Rhabdomyomatous Differentiation

David Suster; Howard D Epstein; Daryl Pearlstein; Saul Suster

doi:10.1097/PAP.0000000000000218

Selected Case From the Arkadi M. Rywlin International Pathology Slide Seminar: Atypical Thymoma With Rhabdomyomatous Differentiation

Adv Anat Pathol. 2019 Jan;26(1):64-68. doi: 10.1097/PAP.0000000000000218.

Authors

David Suster¹, Howard D Epstein², Daryl Pearlstein², Saul Suster³

Affiliations

¹ Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
² Departments of Pathology and Surgery, Hoag Memorial Hospital, Newport Beach, CA.
³ Department of Pathology, Medical College of Wisconsin, Milwaukee, WI.

PMID: 30300145
DOI: 10.1097/PAP.0000000000000218

Abstract

Thymic epithelial neoplasms with foci of rhabdomyomatous differentiation are rare. A case is presented of a primary thymic epithelial neoplasm showing the features of an atypical spindle cell thymoma that contained foci of bland-appearing rhabdomyomatous cells. The histologic and immunohistochemical features of this tumor are discussed along with a review of the literature and the comments from the AMR members to the case.

Publication types

Case Reports

MeSH terms

Aged
Cell Differentiation / physiology
Diagnosis, Differential
Humans
Male
Neoplasms, Glandular and Epithelial / complications
Neoplasms, Glandular and Epithelial / diagnosis
Neoplasms, Glandular and Epithelial / pathology*
Rhabdomyosarcoma / complications
Rhabdomyosarcoma / pathology*
Thymoma / complications
Thymoma / diagnosis
Thymoma / pathology*
Thymus Neoplasms / complications
Thymus Neoplasms / diagnosis
Thymus Neoplasms / pathology*

Supplementary concepts

Thymic epithelial tumor