Proteolysis Targeting Chimera (PROTAC): A Paradigm-Shifting Approach in Small Molecule Drug Discovery

Curr Top Med Chem. 2018;18(16):1354-1356. doi: 10.2174/1568026618666181010101922.

Authors

Pingyuan Wang¹, Jia Zhou¹

Affiliation

¹ Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555, United States.

PMID: 30306871
DOI: 10.2174/1568026618666181010101922

No abstract available

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Publication types

Review

MeSH terms

Drug Discovery*
Humans
Ligands
Proteolysis*
Small Molecule Libraries* / chemistry
Small Molecule Libraries* / pharmacology

Substances

Ligands
Small Molecule Libraries