Vaccine Effectiveness Against Lineage-matched and -mismatched Influenza B Viruses Across 8 Seasons in Canada, 2010-2011 to 2017-2018

Clin Infect Dis. 2019 May 2;68(10):1754-1757. doi: 10.1093/cid/ciy876.

Abstract

Vaccine effectiveness (VE) against influenza B was derived separately for Victoria and Yamagata lineages across 8 seasons (2010-2011 to 2017-2018) in Canada when trivalent influenza vaccine was predominantly used. VE was ≥50% regardless of lineage match to circulating viruses, except when the vaccine strain was unchanged from the prior season.

Keywords: cross-protection; influenza B virus; influenza vaccine effectiveness; lineage; repeat vaccination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Canada
  • Child
  • Child, Preschool
  • Cross Protection / immunology*
  • Databases, Factual
  • Epidemiological Monitoring
  • Female
  • Humans
  • Immunogenicity, Vaccine
  • Infant
  • Influenza B virus / classification*
  • Influenza Vaccines / immunology*
  • Influenza Vaccines / standards
  • Influenza, Human / prevention & control*
  • Male
  • Middle Aged
  • Seasons*
  • Vaccine Potency*
  • Young Adult

Substances

  • Influenza Vaccines

Grants and funding