Risk Factors for Small Bowel Obstruction After Laparoscopic Ileal Pouch-Anal Anastomosis for Inflammatory Bowel Disease: A Multivariate Analysis in Four Expert Centres in Europe

J Crohns Colitis. 2019 Mar 26;13(3):294-301. doi: 10.1093/ecco-jcc/jjy160.

Abstract

Background and aims: Although laparoscopy is associated with a reduction in adhesions, no data are available about the risk factors for small bowel obstruction [SBO] after laparoscopic ileal pouch-anal anastomosis [IPAA]. Our aims here were to identify the risk factors for SBO after laparoscopic IPAA for inflammatory bowel disease [IBD].

Methods: All consecutive patients undergoing laparoscopic IPAA for IBD in four European expert centres were included and divided into Groups A [SBO during follow-up] and B [no SBO].

Results: From 2005 to 2015, SBO occurred in 41/521 patients [Group A; 8%]. Two-stage IPAA was more frequently complicated by SBO than 3- and modified 2-stage IPAA [12% vs 7% and 4%, p = 0.04]. After multivariate analysis, postoperative morbidity (odds ratio [OR] = 3, 95% confidence interval [CI] = 1.5-7, p = 0.002), stoma-related complications [OR = 3, 95% CI = 1-6, p = 0.03] and long-term incisional hernia [OR = 6, 95% CI = 2-18, p = 0.003] were predictive factors for SBO, while subtotal colectomy as first surgery was an independent protective factor [OR = 0.4, 95% CI = 0.2-0.8, p = 0.002]. In the subgroup of patients receiving restorative proctocolectomy as first operation, stoma-related or other surgical complications and long-term incisional hernia were predictive of SBO. In the patient subgroup of subtotal colectomy as first operation, postoperative morbidity and long-term incisional hernia were predictive of SBO, whereas ulcerative colitis and a laparoscopic approach during the second surgical stage were protective factors.

Conclusions: We found that SBO occurred in less than 10% of patients after laparoscopic IPAA. The study also suggested that modified 2-stage IPAA could potentially be safer than procedures with temporary ileostomy [2- and 3-stage IPAA] in terms of SBO occurrence.

Keywords: Laparoscopic ileal pouch–anal anastomosis; modified 2-stage; small bowel obstruction.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Colectomy / adverse effects
  • Colitis, Ulcerative / surgery*
  • Crohn Disease / surgery*
  • Europe
  • Female
  • Humans
  • Ileostomy / adverse effects
  • Incisional Hernia / epidemiology
  • Intestinal Obstruction / epidemiology
  • Intestinal Obstruction / etiology*
  • Intestine, Small
  • Laparoscopy / adverse effects
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Proctocolectomy, Restorative / adverse effects*
  • Proctocolectomy, Restorative / methods
  • Protective Factors
  • Risk Factors