Sclerosing Odontogenic Carcinoma with Local Recurrence: Case Report and Review of Literature

Emilija Todorovic; Eric Berthelet; Robert O'Connor; J Scott Durham; Eric Tran; Monty Martin; Malcolm M Hayes; Tony L Ng

doi:10.1007/s12105-018-0975-6

Sclerosing Odontogenic Carcinoma with Local Recurrence: Case Report and Review of Literature

Head Neck Pathol. 2019 Sep;13(3):371-377. doi: 10.1007/s12105-018-0975-6. Epub 2018 Oct 12.

Authors

Emilija Todorovic^{1

2}, Eric Berthelet³, Robert O'Connor^{1

2}, J Scott Durham⁴, Eric Tran³, Monty Martin⁵, Malcolm M Hayes⁶, Tony L Ng^{7

8}

Affiliations

¹ Department of Pathology and Laboratory Medicine, Vancouver General Hospital, 855 West 12th Avenue, Vancouver, BC, Canada.
² Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
³ Department of Radiation Oncology, BC Cancer Agency, University of British Columbia, Vancouver, BC, Canada.
⁴ Division of Otolaryngology - Head and Neck Surgery, Vancouver General Hospital, Vancouver, BC, Canada.
⁵ Department of Radiology, BC Cancer Agency, Vancouver, BC, Canada.
⁶ Department of Pathology and Laboratory Medicine, BC Cancer Agency, Vancouver, BC, Canada.
⁷ Department of Pathology and Laboratory Medicine, Vancouver General Hospital, 855 West 12th Avenue, Vancouver, BC, Canada. [email protected].
⁸ Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. [email protected].

Abstract

Sclerosing odontogenic carcinoma is a rare locally destructive neoplasm with many histologic mimics. Here the diagnostic challenges are presented of a case of sclerosing odontogenic carcinoma with variable histologic features, including unusual and unexpected negative immunostaining for CK19.

Keywords: Case report; Review of literature; Sclerosing odontogenic carcinoma.

Publication types

Case Reports
Review

MeSH terms

Carcinoma / pathology*
Carcinoma / therapy
Carcinoma, Hepatocellular
Humans
Liver Neoplasms
Male
Maxillary Neoplasms / pathology*
Maxillary Neoplasms / therapy
Middle Aged
Neoplasm Recurrence, Local / pathology
Neoplasm Recurrence, Local / radiotherapy
Neoplasms, Second Primary / pathology*
Neoplasms, Second Primary / therapy
Odontogenic Tumors / pathology*
Odontogenic Tumors / therapy