Unexpected response to cisplatin rechallenge after immune checkpoint inhibitors in patients with metastatic urothelial carcinoma refractory to platinum regimen

Eur J Cancer. 2018 Nov:104:236-238. doi: 10.1016/j.ejca.2018.09.002. Epub 2018 Oct 11.
No abstract available

Publication types

  • Letter
  • Multicenter Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • B7-H1 Antigen / antagonists & inhibitors*
  • Carboplatin / administration & dosage
  • Carcinoma, Transitional Cell / drug therapy
  • Carcinoma, Transitional Cell / secondary*
  • Carcinoma, Transitional Cell / surgery
  • Chemotherapy, Adjuvant
  • Cisplatin / administration & dosage
  • Cisplatin / therapeutic use*
  • Combined Modality Therapy
  • Drug Resistance, Neoplasm
  • Drug Substitution
  • Female
  • Humans
  • Immunotherapy*
  • Male
  • Middle Aged
  • Neoadjuvant Therapy
  • Neoplasm Proteins / antagonists & inhibitors*
  • Programmed Cell Death 1 Receptor / antagonists & inhibitors*
  • Progression-Free Survival
  • Retrospective Studies
  • Salvage Therapy*
  • Urologic Neoplasms / drug therapy*
  • Urologic Neoplasms / surgery

Substances

  • B7-H1 Antigen
  • CD274 protein, human
  • Neoplasm Proteins
  • PDCD1 protein, human
  • Programmed Cell Death 1 Receptor
  • Carboplatin
  • Cisplatin