Survival after out-of-hospital cardiac arrest is associated with area-level socioeconomic status

Heart. 2019 Apr;105(8):632-638. doi: 10.1136/heartjnl-2018-313838. Epub 2018 Oct 16.

Abstract

Objective: Out-of-hospital cardiac arrest (OHCA) is a major cause of death in the Western world. In this study we aimed to investigate the relationship between area-level socioeconomic status (SES) and 30-day survival after OHCA. We hypothesised that high SES at an area level is associated with an improved chance of 30-day survival.

Methods: Patients with OHCA in Stockholm County between 1 January 2006 and 31 December 2015 were analysed retrospectively. To quantify area-level SES, we linked the patient's home address to 250 × 250/1000 × 1000 meter grids with aggregated information about income and education. We constructed multivariable logistic regression models in which area-level SES measures were adjusted for age, sex, emergency medical services response time, witnessed status, initial rhythm, aetiology, location and year of cardiac arrest.

Results: We included 7431 OHCAs. There was significantly greater 30-day survival (p=0.003) in areas with a high proportion of university-educated people. No statistically significant association was seen between median disposable income and 30-day survival. The adjusted OR for 30-day survival among patients in the highest educational quintile was 1.70 (95% CI 1.15 to 2.51) compared with patients in the lowest educational quintile. We found no significant interaction for sex. Positive trend with increasing area-level education was seen in both men and women but the trend was only statistically significant among men (p=0.012) CONCLUSIONS: Survival to 30 days after OHCA is positively associated with the average educational level of the residential area. Area-level income does not independently predict 30-day survival after OHCA.

Keywords: cardiac arrest.

MeSH terms

  • Aged
  • Cardiopulmonary Resuscitation* / methods
  • Cardiopulmonary Resuscitation* / statistics & numerical data
  • Correlation of Data
  • Educational Status*
  • Emergency Medical Services / statistics & numerical data
  • Female
  • Humans
  • Income / statistics & numerical data
  • Male
  • Middle Aged
  • Out-of-Hospital Cardiac Arrest* / mortality
  • Out-of-Hospital Cardiac Arrest* / therapy
  • Protective Factors
  • Residence Characteristics / statistics & numerical data*
  • Risk Factors
  • Sex Factors
  • Social Class
  • Survival Analysis
  • Sweden / epidemiology
  • Time-to-Treatment / standards
  • Time-to-Treatment / statistics & numerical data