Generalized fixed drug eruption mimicking CD8+ cutaneous T-cell lymphoma in HIV

J Cutan Pathol. 2019 Feb;46(2):134-137. doi: 10.1111/cup.13376. Epub 2018 Nov 14.

Abstract

We present a case of a widespread fixed drug eruption histologically mimicking CD8 positive cutaneous T-cell lymphoma (CTCL). CTCL has several potential histological and clinical mimics, and accurate diagnosis relies on a combination of clinicopathological correlation and molecular studies. We add generalized fixed drug eruption to the list of possible CTCL mimics.

Keywords: cutaneous T-cell lymphoma; fixed drug eruption; pseudolymphoma.

Publication types

  • Case Reports

MeSH terms

  • Anti-Retroviral Agents / administration & dosage
  • Anti-Retroviral Agents / adverse effects*
  • CD8-Positive T-Lymphocytes / pathology*
  • Drug Eruptions / pathology*
  • HIV Infections / drug therapy*
  • HIV Infections / pathology
  • HIV-1*
  • Humans
  • Lymphoma, T-Cell, Cutaneous* / chemically induced
  • Lymphoma, T-Cell, Cutaneous* / pathology
  • Male
  • Middle Aged
  • Skin Neoplasms* / chemically induced
  • Skin Neoplasms* / pathology

Substances

  • Anti-Retroviral Agents