Co-expression of AML1-ETO and PML-RARa following treatment of de novo acute myeloid leukemia with AML1-ETO

Leuk Lymphoma. 2019 May;60(5):1316-1319. doi: 10.1080/10428194.2018.1520991. Epub 2018 Oct 17.

Authors

Shuling Zhang¹, Wei Zhou², Yanchun Li³, Shuili Yu⁴, Mingming Xue¹, Yanhong Qiao¹, Jinli Jian¹, Bei Liu^{1

5}, Degui Wang⁶

Affiliations

¹ a The First Clinical Medical College, Lanzhou University , Lanzhou , Gansu , China.
² b Respiratory medicine department , Beijing Geriatric Hospital , Beijing , China.
³ c Department of Hematology , Shanxi Provincial People's Hospital , Xian , Shanxi , China.
⁴ d People's Hospital of Jingyuan County, Jingyuan , Baiyin , Gansu , China.
⁵ e Department of Hematology , The First Affiliated Hospital, Lanzhou University , Lanzhou , Gansu , China.
⁶ f Department of Anatomy and Histology , Lanzhou University, School of Basic Medical Sciences , Lanzhou , China.

PMID: 30328750
DOI: 10.1080/10428194.2018.1520991

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Abnormal Karyotype
Adolescent
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biomarkers, Tumor*
Bone Marrow / metabolism
Bone Marrow / pathology
Core Binding Factor Alpha 2 Subunit / genetics*
Core Binding Factor Alpha 2 Subunit / metabolism
Gene Expression Regulation, Leukemic*
Humans
Immunophenotyping
In Situ Hybridization, Fluorescence
Leukemia, Myeloid, Acute / diagnosis
Leukemia, Myeloid, Acute / drug therapy
Leukemia, Myeloid, Acute / genetics*
Male
Oncogene Proteins, Fusion / genetics*
Oncogene Proteins, Fusion / metabolism
RUNX1 Translocation Partner 1 Protein / genetics*
RUNX1 Translocation Partner 1 Protein / metabolism
Translocation, Genetic

Substances

AML1-ETO fusion protein, human
Biomarkers, Tumor
Core Binding Factor Alpha 2 Subunit
Oncogene Proteins, Fusion
RUNX1 Translocation Partner 1 Protein
promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein