Evidence of Subclavian Vein Thrombosis on First-Pass 18FDG PET in a Patient with Relapsing Upper Mediastinum Lymphoma

Nucl Med Mol Imaging. 2018 Oct;52(5):398-400. doi: 10.1007/s13139-018-0541-x. Epub 2018 Aug 20.

Abstract

Baseline 18F-FDG PET was performed in a 74-year-old patient with relapsing upper mediastinum lymphoma. Left subclavian thrombosis was suspected on prior contrast-enhanced CT. Dynamic PET imaging was achieved during 3 min after IV injection of 18F-FDG to the left arm in order to further assess left subclavian vein permeability. The 20-s dynamic frame at 1 min after injection confirmed the absence of flow in the left subclavian vein and evidenced the derivation of 18F-FDG through left axillary, then superficial, then right internal mammary collaterals to the superior vena cava, hence confirming the subclavian thrombosis.

Keywords: Deep vein thrombosis; FDG PET; First-pass; Lymphoma.