Machine-Assisted Genotype Update System (MAGUS) for Inherited Cardiomyopathies

Circ Cardiovasc Qual Outcomes. 2018 Oct;11(10):e004835. doi: 10.1161/CIRCOUTCOMES.118.004835.

Authors

Nikolaos Papoutsidakis¹, Stephen B Heitner², Meghan C Mannello², Anna Rodonski³, William Campbell³, Kylie McElheran², Daniel L Jacoby¹

Affiliations

¹ Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT (N.P., D.L.J.).
² Oregon Health and Science University, Knight Cardiovascular Institute Hypertrophic Cardiomyopathy and Cardiogenetics Centers, Portland (S.B.H., M.C.M., K.E.).
³ Yale New Haven Hospital Heart and Vascular Center, New Haven, CT (A.R.).

PMID: 30354577
DOI: 10.1161/CIRCOUTCOMES.118.004835

No abstract available

Keywords: cardiomyopathies; computational biology; genetic testing; genetics; humans.

MeSH terms

Arrhythmogenic Right Ventricular Dysplasia / classification
Arrhythmogenic Right Ventricular Dysplasia / diagnosis
Arrhythmogenic Right Ventricular Dysplasia / genetics*
Cardiomyopathy, Dilated / classification
Cardiomyopathy, Dilated / diagnosis
Cardiomyopathy, Dilated / genetics*
Cardiomyopathy, Hypertrophic, Familial / classification
Cardiomyopathy, Hypertrophic, Familial / diagnosis
Cardiomyopathy, Hypertrophic, Familial / genetics*
Computational Biology / methods*
Data Mining / methods*
Genetic Predisposition to Disease
Genetic Testing / methods*
Genetic Variation*
Heredity
High-Throughput Nucleotide Sequencing
Humans
Machine Learning*
Pedigree
Phenotype
Predictive Value of Tests
Prognosis
Reproducibility of Results
Risk Assessment
Risk Factors