A fatal case of enterovirus infection with secondary hemophagocytosis-case report with review of literature

APMIS. 2018 Nov;126(11):877-882. doi: 10.1111/apm.12892.

Abstract

Enterovirus is a common viral infection, which can affect multiple organ systems with an array of clinical presentation such as meningitis, encephalitis, myocarditis, and disseminated infections. The illness is usually asymptomatic and self-limited but few cases can be severe and life-threatening especially when associated with hemophagocytosis. We discuss a fatal case of disseminated enterovirus infection and the histomorphological features of the infection.

Keywords: Enterovirus; encephalitis; hemophagocytosis; myocarditis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Enterovirus / pathogenicity*
  • Enterovirus / physiology
  • Enterovirus Infections / complications
  • Enterovirus Infections / diagnosis
  • Enterovirus Infections / pathology
  • Enterovirus Infections / virology*
  • Fatal Outcome
  • Female
  • Humans
  • Infant, Newborn
  • Lymphohistiocytosis, Hemophagocytic / complications
  • Lymphohistiocytosis, Hemophagocytic / diagnosis
  • Lymphohistiocytosis, Hemophagocytic / pathology
  • Lymphohistiocytosis, Hemophagocytic / virology*
  • Male