Erythema ab igne in patients with sickle cell disease

Pediatr Hematol Oncol. 2018 Apr;35(3):225-230. doi: 10.1080/08880018.2018.1516838. Epub 2018 Oct 25.

Abstract

Erythema ab igne (EAI) is an asymptomatic dermatosis caused by prolonged exposure to localized heat. Affected areas have net-like hyperpigmentation that may resemble more serious conditions such as livedo racemosa or vasculitis. We report three cases of EAI in pediatric sickle cell disease (SCD) patients who were initially suspected of having a more severe, life-threatening disorder before Dermatology was consulted. Clinicians caring for pediatric SCD patients who regularly use heating pads/devices for pain relief should consider EAI in the differential diagnosis of large areas of net-like hyperpigmentation. This paper aims to increase recognition of EAI and patient education on safe practices while using heating pads.

Keywords: Sickle cell disease; erythema ab igne; heating pad; net-like hyperpigmentation; reticular hyperpigmentation.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Anemia, Sickle Cell / complications*
  • Anemia, Sickle Cell / pathology
  • Erythema / etiology*
  • Female
  • Hot Temperature
  • Humans
  • Hyperpigmentation
  • Skin Diseases / etiology*
  • Young Adult