Endovascular clot retrieval for acute ischaemic stroke in New Zealand

N Z Med J. 2018 Oct 26;131(1484):13-18.

Abstract

Aims: Stroke endovascular clot retrieval (ECR) in patients with large proximal vessel occlusion improves clinical outcomes. We present the New Zealand ECR experience.

Methods: All New Zealand patients treated with ECR since 2011 were included. Patients were considered eligible if they were independent prior to stroke and had proximal intracranial arterial occlusion.

Results: Three hundred and twelve patients [136 women, mean (SD) age of 64 (17) years] from 11 district health boards have been treated between March 2011 and April 2018. There were 260 (83%) patients with anterior and 52 (17%) with posterior circulation arterial occlusion. One hundred and ninety-three (62%) patients were pre-treated with intravenous alteplase. The median time from symptom onset to groin puncture was 210 (range 65-985) minutes. Complete or near-complete recanalisation (Thrombolysis in Cerebral Infarction scores of 3 or 2b) was achieved in 260 of 300 (87%) and the National Institutes of Health Stroke Scale score improved from a median of 18 at baseline to 7 at 24 hours. By day 90, 55% of the anterior circulation patients and 40% of the posterior circulation patients were living independently at home. Mortality rates were 20% for anterior circulation patients and 30% for the posterior circulation patients.

Conclusions: This study has shown that stroke endovascular clot retrieval is being provided safely and effectively in New Zealand. However, there remain discrepancies in service provision, and ongoing regional, inter-regional and inter-sector collaboration is essential to implement comprehensive and equitable ECR services across the country.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Arterial Occlusive Diseases / epidemiology
  • Arterial Occlusive Diseases / therapy
  • Brain Ischemia / epidemiology
  • Brain Ischemia / therapy
  • Endovascular Procedures*
  • Female
  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • New Zealand
  • Severity of Illness Index
  • Stroke / epidemiology
  • Stroke / therapy*
  • Thrombectomy / methods*
  • Thrombolytic Therapy
  • Time-to-Treatment / statistics & numerical data
  • Tissue Plasminogen Activator / therapeutic use
  • Young Adult

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator