The impact and prospect of natural product discovery in agriculture: New technologies to explore the diversity of secondary metabolites in plants and microorganisms for applications in agriculture

Yan Yan; Qikun Liu; Steven E Jacobsen; Yi Tang

doi:10.15252/embr.201846824

The impact and prospect of natural product discovery in agriculture: New technologies to explore the diversity of secondary metabolites in plants and microorganisms for applications in agriculture

EMBO Rep. 2018 Nov;19(11):e46824. doi: 10.15252/embr.201846824. Epub 2018 Oct 25.

Authors

Yan Yan¹, Qikun Liu², Steven E Jacobsen², Yi Tang^{1

3}

Affiliations

¹ Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, CA, USA.
² Department of Molecular, Cell, and Developmental Biology, Howard Hughes Medical Institute, University of California Los Angeles, Los Angeles, CA, USA.
³ Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, CA, USA.

Abstract

Natural products from plants and microorganisms are potent bioactive molecules that have been used in medicine, agriculture and cosmetics. Genomics and synthetic biology offer new tools to further explore their diversity for applications as fungicides or herbicides.

MeSH terms

Agriculture / methods*
Biological Products / chemistry
Biological Products / metabolism*
Biological Products / pharmacology*
Drug Resistance, Microbial / genetics*
Fungicides, Industrial / pharmacology
Genome, Microbial
Genome, Plant
Metabolic Engineering
Microorganisms, Genetically-Modified
Multigene Family
Pesticides / pharmacology
Plants / genetics
Plants / metabolism*
Secondary Metabolism

Substances

Biological Products
Fungicides, Industrial
Pesticides

Grants and funding

R35 GM118056/GM/NIGMS NIH HHS/United States