Relationships between blood pressure measurements and target organ damage: Data from the Korea women's chest pain registry

J Clin Hypertens (Greenwich). 2018 Dec;20(12):1724-1730. doi: 10.1111/jch.13417. Epub 2018 Oct 25.

Abstract

This study was performed to investigate the association between four BP measurements (systolic blood pressure [SBP], diastolic blood pressure [DBP], mean arterial pressure [MAP], and pulse pressure [PP]) and four TOD parameters (left ventricular mass index [LVMI], E/e', estimated glomerular filtration rate [eGFR], and obstructive coronary artery disease [CAD]). Data were obtained from a nation-wide registry, composed of 652 patients (471 women, 58.4 ± 10.5 years) with suspected CAD who underwent elective invasive coronary angiography (CAG). A total of 217 patients (33.2%) had obstructive CAD (≥50%). In multivariable analyses, E/e' was associated with SBP, MAP and PP, and CAD was associated with SBP and PP (P < 0.05 for each). All four BP measurements were not associated with LVMI and eGFR (P > 0.05 for each). In patients undergoing elective invasive CAG, SBP, and PP had stronger relationships with E/e' and CAD than DBP and MAP.

Keywords: blood pressure measurements; coronary angiography; target organ damage.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Arterial Pressure / physiology
  • Blood Pressure / physiology*
  • Blood Pressure Determination / methods*
  • Chest Pain / diagnosis*
  • Chest Pain / physiopathology
  • Coronary Angiography / methods
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / physiopathology
  • Cross-Sectional Studies
  • Echocardiography / methods
  • Female
  • Glomerular Filtration Rate / physiology
  • Heart Ventricles / anatomy & histology
  • Heart Ventricles / diagnostic imaging*
  • Heart Ventricles / physiopathology
  • Humans
  • Middle Aged
  • Prospective Studies
  • Registries
  • Republic of Korea / epidemiology