Confusional state in a pregnant woman: A case of NMDA receptor encephalitis during pregnancy

J Neuroimmunol. 2018 Dec 15:325:29-31. doi: 10.1016/j.jneuroim.2018.10.008. Epub 2018 Oct 19.

Abstract

We report the case of a pregnant female presenting with behavioral change and hallucinations followed by focal seizures with impaired awareness. EEG revealed generalized slowing interspersed with extreme delta-brush pattern and MRI brain was normal. Both Serum and CSF anti-N-methyl-d-aspartate receptor (NMDAR) antibodies were positive. Patient had a prolonged hospital stay with full recovery and delivered a healthy baby, highlighting the significance of early diagnosis and management in this disorder.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis / complications*
  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis / diagnostic imaging*
  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis / psychology
  • Confusion / complications*
  • Confusion / diagnostic imaging*
  • Confusion / psychology
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications / diagnostic imaging*
  • Pregnancy Complications / psychology