Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution
Nat Genet
.
2018 Dec;50(12):1620-1623.
doi: 10.1038/s41588-018-0217-6.
Authors
Thomas O McDonald
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1
2
3
4
,
Shaon Chakrabarti
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1
2
4
,
Franziska Michor
5
6
7
8
Affiliations
1
Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
2
Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
3
Center for Cancer Evolution, Dana-Farber Cancer Institute, Boston, MA, USA.
4
Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
5
Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
[email protected]
.
6
Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
[email protected]
.
7
Center for Cancer Evolution, Dana-Farber Cancer Institute, Boston, MA, USA.
[email protected]
.
8
Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
[email protected]
.
#
Contributed equally.
PMID:
30374067
PMCID:
PMC6467055
DOI:
10.1038/s41588-018-0217-6
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
Comment
MeSH terms
Genetic Drift*
Humans
Neoplasms*
Grants and funding
U54 CA193461/CA/NCI NIH HHS/United States