Exhaled carbon monoxide levels correlate with incidence of oral mucosal lesions independent of smoking status

Int J Environ Health Res. 2019 Jun;29(3):290-300. doi: 10.1080/09603123.2018.1541442. Epub 2018 Oct 30.

Abstract

Carbon monoxide (CO) is an important component of tobacco smoke, but also environmental toxicity. This study analyzed possible correlation between exhaled CO level and oral health indicators in two geographically distributed populations during health-promoting public events organized for local communities in cities with high and low environmental pollution in Poland (907 patients). Self-reported, instructor-led, oral health questionnaire was developed to monitor current and previous mucosal lesion incidence. Exhaled CO correlated with subjects smoking status and environmental CO exposure: highest in smoking inhabitants of Krakow (12 ppm), with lower levels in smokers from Kozienice (6.5 ppm) and non-smokers from Krakow (6 ppm), and lowest for Kozienice non-smokers (2 ppm) (p < 0.001). After propensity score matching and adjustment for smoking status, demography and comorbidities odds ratio for mucosal lesion incidence was 1.46 (1.31-1.63), p < 0.001) per 1 ppm increase of exhaled CO level. This result might implicate a possible role of environmental pollution factors in oral health pathology.

Keywords: Carbon monoxide; community setting; oral mucosal lesions; smoking status.

MeSH terms

  • Adult
  • Air Pollution
  • Carbon Monoxide / analysis*
  • Comorbidity
  • Exhalation
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Mouth Diseases / epidemiology*
  • Mouth Mucosa / pathology*
  • Odds Ratio
  • Poland
  • Smoking / epidemiology
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Carbon Monoxide