UPLC-Orbitrap-MS/MS combined with chemometrics establishes variations in chemical components in green tea from Yunnan and Hunan origins

Food Chem. 2018 Nov 15:266:534-544. doi: 10.1016/j.foodchem.2018.06.056. Epub 2018 Jun 13.

Abstract

Multi-components of green tea from different origins were identified by UPLC-Orbitrap-MS/MS, including alkaloids, amino acids, catechins, flavones, flavone glycosides, phenolic acids and theaflavins. Quantitative chemical profiles of 72 samples of Yunnan green tea (YGT) and Hunan green tea (HGT) established the influence of origin on green tea. In addition, three variable selection methods, based on partial least squares-discriminant analysis (PLS-DA), were employed to screen characteristic components of YGT and HGT. The results of variable importance on projection (VIP) method showed better performance than coefficients β and the least absolute shrinkage and selection operator (LASSO) for this dataset. Three characteristic components, named, gallocatechin gallate (GCG), epicatechin-(4β → 8)-epigallocatechin-3-O-gallate, and vitexin were selected by VIP, with a correct rate of 98.61% and an AUC value of 0.9706. The results indicated that the combination of UPLC-Orbitrap-MS/MS and chemometrics could serve as a valid strategy to analyze complex analytical objects, such as green tea.

Keywords: 1,4,6-Trigalloyl-β-d-glucopyranose (PubChem CID: 14284610); Chemometrics; Epicatechin gallate (PubChem CID: 107905); Gallocatechin gallate (PubChem CID: 199472); Green tea; Kaempferol 3-O-glucoside (PubChem CID: 5282102); Quantitative chemical profile; Theaflavin (PubChem CID: 114777); Theaflavin 3,3′-digallate (PubChem CID: 58252602); Theaflavin 3-gallate (PubChem CID: 102115506); Theaflavin 3′-gallate (PubChem CID: 467321); Tryptophan (PubChem CID: 6305); UPLC–Orbitrap–MS/MS; Vitexin (PubChem CID: 5280441).

MeSH terms

  • Apigenin / analysis
  • Catechin / analogs & derivatives
  • Catechin / analysis
  • China
  • Chromatography, High Pressure Liquid
  • Cluster Analysis
  • Discriminant Analysis
  • Plant Extracts / analysis*
  • Plant Extracts / chemistry
  • Principal Component Analysis
  • Tandem Mass Spectrometry / methods*
  • Tea / chemistry*
  • Tea / metabolism

Substances

  • Plant Extracts
  • Tea
  • gallocatechin gallate
  • Apigenin
  • Catechin
  • vitexin
  • epigallocatechin gallate