More than Just a "Motor": Recent Surprises from the Frontal Cortex

J Neurosci. 2018 Oct 31;38(44):9402-9413. doi: 10.1523/JNEUROSCI.1671-18.2018.

Abstract

Motor and premotor cortices are crucial for the control of movements. However, we still know little about how these areas contribute to higher-order motor control, such as deciding which movements to make and when to make them. Here we focus on rodent studies and review recent findings, which suggest that-in addition to motor control-neurons in motor cortices play a role in sensory integration, behavioral strategizing, working memory, and decision-making. We suggest that these seemingly disparate functions may subserve an evolutionarily conserved role in sensorimotor cognition and that further study of rodent motor cortices could make a major contribution to our understanding of the evolution and function of the mammalian frontal cortex.

Keywords: action selection; action timing; active sensing; decision-making; frontal cortex; motor control.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Humans
  • Motor Cortex / physiology*
  • Movement / physiology*
  • Prefrontal Cortex / physiology*
  • Touch / physiology*
  • Vibrissae / innervation
  • Vibrissae / physiology