Autoimmunity to bactericidal/permeability-increasing protein in bronchiectasis exhibits a requirement for Pseudomonas aeruginosa IgG response

Eur Respir J. 2019 Feb 7;53(2):1801891. doi: 10.1183/13993003.01891-2018. Print 2019 Feb.

Affiliations

¹ Dept of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
² Center for Infectious Disease Studies, OHSU-PSU School of Public Health, Portland, OR, USA.
³ Division of Pulmonology, Dept of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
⁴ The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH, USA.
⁵ Division of Rheumatology, Dept of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.

PMID: 30385530
DOI: 10.1183/13993003.01891-2018

No abstract available

Publication types

Letter
Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Antimicrobial Cationic Peptides / immunology*
Autoantibodies / immunology
Autoimmunity*
Blood Proteins / immunology*
Bronchiectasis / immunology
Bronchiectasis / microbiology*
Cystic Fibrosis / immunology
Cystic Fibrosis / microbiology*
Cystic Fibrosis Transmembrane Conductance Regulator / genetics
Enzyme-Linked Immunosorbent Assay
Genetic Predisposition to Disease
Humans
Immunoglobulin G / immunology*
Inflammation
Mutation
New Hampshire
Oregon
Pseudomonas Infections / immunology*
Pseudomonas Infections / microbiology
Pseudomonas aeruginosa*

Substances

Antimicrobial Cationic Peptides
Autoantibodies
Blood Proteins
CFTR protein, human
Immunoglobulin G
bactericidal permeability increasing protein
Cystic Fibrosis Transmembrane Conductance Regulator