[Epidemiological, clinical, histological and therapeutic features of primary digestive cancers in Burkina Faso]

Bull Cancer. 2018 Dec;105(12):1119-1125. doi: 10.1016/j.bulcan.2018.09.001. Epub 2018 Nov 2.
[Article in French]

Abstract

Objective: To study the epidemiology and histology of primary digestive cancers in semi-urban areas in Burkina Faso.

Methods: This was a descriptive study over 5 years conducted simultaneously in 2 regional hospitals in Burkina Faso. It included all patients treated for primary digestive cancers.

Results: A total of 352 were included. The average age of the patients was 44.3 years. Patients aged between 30 and 49 years accounted for 44.6%. There were 175 male patients (49.7%). In the patient's history, we found 6 cases of ulcerative colitis, 2 cases of colonic adenoma, and 5 cases of hepatic cirrhosis. The average consultation time was 138 days. In 70 cases (19.9%), the cancer was discovered at a stage of complication. The most affected organs were the colon and rectum (36.7%), the stomach (21.9%) and the pancreas (19.0%). The most common histological type of cancer was adenocarcinoma (67.6%). One hundred and forty-four patients (40.9%) were diagnosed at stage 3 and 65 others (18.5%) at stage 4 of TMN staging. Therapeutically, surgery was used in 307 patients (87.2%) and chemotherapy in 63 cases (17.9%). The one-year mortality rate was 29%.

Conclusion: In Burkina Faso rural area, primary digestive cancers occur in young patients with no predominance of sex. Colorectal cancer remains the most common.

Keywords: Adenocarcinoma; Adénocarcinome; Burkina Faso; Cancer digestif; Digestive cancer; Surgical treatment; Traitement chirurgical.

Publication types

  • Multicenter Study

MeSH terms

  • Adenocarcinoma / epidemiology
  • Adenocarcinoma / pathology
  • Adenocarcinoma / therapy
  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Burkina Faso / epidemiology
  • Child
  • Child, Preschool
  • Colonic Neoplasms / epidemiology
  • Colonic Neoplasms / pathology
  • Colonic Neoplasms / therapy
  • Delayed Diagnosis
  • Female
  • Gastrointestinal Neoplasms* / epidemiology
  • Gastrointestinal Neoplasms* / pathology
  • Gastrointestinal Neoplasms* / therapy
  • Humans
  • Male
  • Middle Aged
  • Pancreatic Neoplasms / epidemiology
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / therapy
  • Rectal Neoplasms / epidemiology
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / therapy
  • Sex Distribution
  • Stomach Neoplasms / epidemiology
  • Stomach Neoplasms / pathology
  • Stomach Neoplasms / therapy
  • Young Adult