18F-FDG PET/CT in locally advanced cervical cancer: A review

Rev Esp Med Nucl Imagen Mol (Engl Ed). 2019 Jan-Feb;38(1):59-68. doi: 10.1016/j.remn.2018.08.004. Epub 2018 Nov 11.
[Article in English, Spanish]

Abstract

Cervical cancer is the second most common gynecological cancer worldwide. In locally advanced cervical cancer, 18F-FDG PET/CT has become important in the initial staging, particularly in the detection of nodal and distant metastasis, aspects with treatment implications and prognostic value. The aims of this study were to review the role of 18F-FDG PET/CT in uterine cervical cancer, according to the guidelines of the main scientific institutions (FIGO, NCCN, SEGO, SEOM, ESGO, and ESMO) and its diagnostic accuracy compared to conventional radiological techniques, as well as to review the acquisition protocol and its utility in radiotherapy planning, response assessment and detection of recurrence.

Keywords: (18)F-FDG PET/CT; Cervical cancer; Cáncer de cérvix; Estadificación; PET/TC con (18)F-FDG; Planificación de radioterapia; Radiotherapy planning; Recidiva; Recurrence; Response; Respuesta; Staging.

Publication types

  • Review

MeSH terms

  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Lymphatic Metastasis
  • Neoplasm Staging
  • Positron Emission Tomography Computed Tomography* / methods
  • Practice Guidelines as Topic
  • Radiopharmaceuticals*
  • Uterine Cervical Neoplasms / diagnostic imaging*
  • Uterine Cervical Neoplasms / pathology

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18