A stereoselective synthesis of (+)-boronolide

Tetrahedron Lett. 2000 Feb 12;41(7):1003-1006. doi: 10.1016/S0040-4039(99)02246-7. Epub 2000 Jun 22.

Abstract

A stereoselective synthesis of (+)-boronolide is described. The key steps involve a stereoselective reduction of an α-hydroxy ketone, allylation of an α-hydroxy aldehyde and a ring-closing olefin metathesis of a homoallylic alcohol derived acrylate ester utilizing Grubbs' catalyst.