Midturbinate Swabs Are Comparable to Nasopharyngeal Swabs for Quantitative Detection of Respiratory Syncytial Virus in Infants

J Pediatric Infect Dis Soc. 2019 Dec 27;8(6):554-558. doi: 10.1093/jpids/piy115.

Abstract

Nasopharyngeal (NP) swabs are generally used to detect respiratory syncytial virus (RSV) in infants. However, midturbinate (MT) swabs may provide comparable results. In this study, we enrolled hospitalized infants aged <24 months with RSV and collected NP and MT swabs. The resulting viral loads measured by real-time reverse-transcription quantitative polymerase chain reaction were similar. Most parents preferred MT swabs over NP swabs.

Keywords: PCR; RSV; bronchiolitis; diagnostics; infants; nasal swab.

MeSH terms

  • Child, Hospitalized
  • Diagnostic Tests, Routine / methods*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Nasopharynx / virology*
  • Real-Time Polymerase Chain Reaction
  • Respiratory Syncytial Virus Infections / diagnosis*
  • Respiratory Syncytial Virus, Human / genetics
  • Respiratory Syncytial Virus, Human / isolation & purification*
  • Specimen Handling / methods
  • Utah
  • Viral Load