Laparoscopy adjuvant total colorectal resection for the treatment of familial adenomatous polyposis (FAP)

Clin Transl Oncol. 2019 Jun;21(6):753-759. doi: 10.1007/s12094-018-1979-0. Epub 2018 Nov 21.

Abstract

Objective: To discuss and evaluate the safety and value of laparoscopy adjuvant total colorectal resection for the treatment of familial adenomatous polyposis (FAP).

Methods: From March 2010 to June 2015, 38 cases were retrospectively analyzed and divided into 2 groups, of which 17 cases used laparoscopy adjuvant total colorectal resection, and 21 cases used conventional laparotomy. Clinical data were obtained, and the safety and prognosis were observed.

Results: Seventeen cases using laparoscopy adjuvant total colorectal resection achieved success with no conversion to laparotomy and intraoperative complications. There was no significant difference in operation time between the two groups. There were significant differences in blood loss, the length of incision, postoperative recovery time of intestinal function and postoperative hospital stay between the two groups (P < 0.05). The trauma in laparoscopy group was less, and could recover faster, and there was no significant difference in complications between the two groups. In addition, there were no recurrence, distant metastasis and death in the follow-up period from 6 to 56 months.

Conclusion: Laparoscopy adjuvant total colorectal resection is more safe and feasible, which has minimal invasion and can recover fast.

Keywords: Familial adenomatous polyposis (FAP); Laparoscopy; Total colorectal resection.

MeSH terms

  • Adenomatous Polyposis Coli / pathology
  • Adenomatous Polyposis Coli / surgery*
  • Adolescent
  • Adult
  • Colorectal Surgery / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Laparoscopy / methods*
  • Length of Stay
  • Male
  • Middle Aged
  • Postoperative Complications*
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult