Deciphering the Sharp Decrease in H7N9 Human Infections

Xu Zhang; Tingting Luo; Yongyi Shen

doi:10.1016/j.tim.2018.10.002

Deciphering the Sharp Decrease in H7N9 Human Infections

Trends Microbiol. 2018 Dec;26(12):971-973. doi: 10.1016/j.tim.2018.10.002. Epub 2018 Oct 25.

Authors

Xu Zhang¹, Tingting Luo¹, Yongyi Shen²

Affiliations

¹ College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
² College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China; Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, Guangzhou 510642, China. Electronic address: [email protected].

PMID: 30472993
DOI: 10.1016/j.tim.2018.10.002

Abstract

The H7N9 virus has caused five waves of human infections since 2013. However, human infections have almost disappeared in the past year. In a recent study, Shi et al. revealed that the usage of a bivalent H5/H7 vaccine successfully prevented chicken infections, and thus prevented, and nearly eliminated, human infections.

Keywords: H7N9; evolution; virulence.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Chickens
China
Hemagglutinin Glycoproteins, Influenza Virus
Humans
Influenza A Virus, H7N9 Subtype / immunology*
Influenza Vaccines*

Substances

Hemagglutinin Glycoproteins, Influenza Virus
Influenza Vaccines