Failure to Rescue After Emergency General Surgery in Geriatric Patients: Does Frailty Matter?

J Surg Res. 2019 Jan:233:397-402. doi: 10.1016/j.jss.2018.08.033. Epub 2018 Sep 17.

Abstract

Background: Failure to rescue (FTR) is considered as an index of quality of care provided by a hospital. However, the role of frailty in FTR remains unclear. We hypothesized that the FTR rate is higher for frail geriatric emergency general surgery (EGS) patients than nonfrail geriatric EGS patients.

Methods: We performed a 3-y (2015-2017) prospective cohort study of all geriatric patients (age ≥ 65 y) requiring EGS. Frailty was calculated by using the EGS-specific Frailty Index (EGSFI) within 24 h of admission. Patients were divided into two groups: frail (FI ≥ 0.325) and nonfrail (FI < 0.325). We defined FTR as death from a major complication. Regression analysis was performed to control for demographics, type of operative intervention, admission vitals, and admission laboratory values.

Results: Three hundred twenty-six geriatric EGS patients were included, of which 38.9% were frail. Frail patients were more likely to be white (P < 0.01) and, on admission, had a higher American Association of Anesthesiologist class (P = 0.03) and lower serum albumin (P < 0.01). However, there was no difference between the groups regarding age (P = 0.54), gender (P = 0.56), admission vitals, and WBC count (P = 0.35). Overall, 26.7% (n = 85) of patients developed in-hospital complications; and mortality occurred in 30% (n = 26) of those patients (i.e., the FTR group). Frail patients had higher rates of FTR (14% vs. 4%, P < 0.001) than nonfrail patients. On regression analysis, after controlling for confounders, frail status was an independent predictor of FTR (OR: 3.4 [2.3-4.6]) in geriatric EGS patients.

Conclusions: Our study demonstrates that in geriatric EGS patients, a frail status independently contributes to FTR and increases the odds of FTR threefold compared with nonfrail status. Thus, it should be included in quality metrics for geriatric EGS patients.

Keywords: EGS; FTR; Failure to rescue; Frailty.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Emergency Service, Hospital / statistics & numerical data
  • Emergency Treatment / adverse effects
  • Emergency Treatment / statistics & numerical data*
  • Failure to Rescue, Health Care / statistics & numerical data*
  • Female
  • Frail Elderly / statistics & numerical data
  • Frailty / complications
  • Frailty / diagnosis*
  • Geriatric Assessment*
  • Hospital Mortality
  • Humans
  • Length of Stay / statistics & numerical data
  • Male
  • Postoperative Complications / etiology
  • Postoperative Complications / mortality
  • Prospective Studies
  • Risk Assessment / methods
  • Risk Factors
  • Surgical Procedures, Operative / adverse effects
  • Surgical Procedures, Operative / statistics & numerical data*