Gene panel testing for breast cancer should not be used to confirm syndromic gene associations

NPJ Genom Med. 2018 Nov 26:3:32. doi: 10.1038/s41525-018-0071-6. eCollection 2018.

D Gareth Evans^{1

2

3}, Sacha J Howell^{3

4}, Ian M Frayling^{5

6}, Juha Peltonen⁷

¹ 1Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, M13 9WL UK.
² 2Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
³ 3The Christie NHS Foundation Trust, Wilmslow Road, Manchester, M20 4BX UK.
⁴ 4Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
⁵ 5All-Wales Medical Genetics Service, Cardiff & Vale University Health Board, University Hospital of Wales, Cardiff, CF14 4XW UK.
⁶ 6Institute of Medical Genetics, Division of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, CF14 4XN UK.
⁷ 7Department of Cell Biology and Anatomy, Institute of Biomedicine, University of Turku, Turku, Finland.

No abstract available