Abstract
Evaluating carcinogenic mechanisms is a challenging part of hazard identification, as mechanistic data are both voluminous and diverse. An evaluation approach based on 10 key characteristics of human carcinogens provides a holistic and unbiased way to tackle this challenge.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
-
Biomarkers / metabolism
-
Carcinogenicity Tests
-
Carcinogens / chemistry*
-
Carcinogens / toxicity
-
DNA Damage / drug effects
-
Epigenesis, Genetic / drug effects
-
Genomic Instability / drug effects
-
Humans
-
Neoplasms / metabolism
-
Neoplasms / pathology
-
Oxidative Stress / drug effects