Efficacy of Clutch Cutter for Standardizing Endoscopic Submucosal Dissection for Early Gastric Cancer: A Propensity Score-Matched Analysis

Digestion. 2019;100(3):201-209. doi: 10.1159/000495287. Epub 2018 Dec 6.

Abstract

Background/aims: The purpose of this study was to evaluate the safety and efficacy of gastric endoscopic submucosal dissection (ESD) using the Clutch Cutter (CC), a scissor-type knife, compared with those of procedures using conventional devices.

Methods: This single-center retrospective study evaluated 237 patients with early gastric cancer: 83 who underwent ESD using the CC group and 154 who underwent ESD using the insulated-tip knife 2 (IT2 group). Clinicopathological features and technical outcomes were compared between the 2 groups using a propensity score-matched analysis.

Results: In 61 pairs of matched patients, there was no significant difference in R0 resection, perforation, or postoperative bleeding between the CC and IT2 groups. Comparisons between the 2 groups showed similar treatment outcomes for an expert endoscopist. Nevertheless, there were significant differences between the 2 groups for nonexperts in terms of self-completion (61.7 and 24.5%, respectively, p < 0.001), mean procedure times (45 and 61 min, respectively, p = 0.002), and mean numbers of intraoperative bleeding points and bleeding points requiring hemostatic forceps (3 and 0 vs. 8 and 3, respectively, p < 0.001).

Conclusion: Better self-completion rates and shorter procedure times were noted for gastric ESD using the CC by nonexperts than for that using IT2, probably due to hemostatic efficacy.

Keywords: Endoscopic submucosal dissection; Gastric cancer; Propensity score-matching; Scissor-type knife.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Loss, Surgical / statistics & numerical data
  • Electrocoagulation / adverse effects
  • Electrocoagulation / instrumentation*
  • Electrocoagulation / methods
  • Endoscopic Mucosal Resection / adverse effects
  • Endoscopic Mucosal Resection / instrumentation*
  • Endoscopic Mucosal Resection / methods
  • Female
  • Gastric Mucosa / injuries
  • Gastric Mucosa / pathology
  • Gastric Mucosa / surgery
  • Gastroscopy / adverse effects
  • Gastroscopy / instrumentation*
  • Gastroscopy / methods
  • Humans
  • Male
  • Middle Aged
  • Operative Time
  • Postoperative Hemorrhage / epidemiology*
  • Postoperative Hemorrhage / etiology
  • Propensity Score
  • Retrospective Studies
  • Stomach Neoplasms / pathology
  • Stomach Neoplasms / surgery*
  • Treatment Outcome