Disseminated Adenovirus Infection After Combined Liver-Kidney Transplantation

Front Cell Infect Microbiol. 2018 Nov 20:8:408. doi: 10.3389/fcimb.2018.00408. eCollection 2018.

Abstract

Human adenovirus (HAdV) infections are well-described after hematopoietic stem cell transplantation but less well understood in solid organ transplantation (SOT). We describe a case of disseminated HAdV type 21 infection 5 months after combined liver-kidney transplantation, expanding the limited literature describing this infection in the SOT population.

Keywords: adenovirus; brincidofovir; epidemiology; immunocompromised host; transplantation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenovirus Infections, Human / blood
  • Adenovirus Infections, Human / drug therapy
  • Adenovirus Infections, Human / transmission*
  • Adenovirus Infections, Human / urine
  • Adenoviruses, Human / genetics
  • Antiviral Agents
  • DNA, Viral
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Kidney Transplantation / adverse effects*
  • Liver Transplantation / adverse effects*
  • Urine / virology
  • Viral Load
  • Viremia / virology

Substances

  • Antiviral Agents
  • DNA, Viral