TRPV4 Is Expressed in Human Hair Follicles and Inhibits Hair Growth In Vitro

J Invest Dermatol. 2019 Jun;139(6):1385-1388. doi: 10.1016/j.jid.2018.11.020. Epub 2018 Dec 6.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cells, Cultured
  • Hair Follicle / cytology
  • Hair Follicle / drug effects
  • Hair Follicle / growth & development*
  • Hair Follicle / metabolism
  • Healthy Volunteers
  • Humans
  • Keratinocytes
  • Leucine / analogs & derivatives
  • Leucine / pharmacology
  • Primary Cell Culture
  • Sulfonamides / pharmacology
  • TRPV Cation Channels / agonists
  • TRPV Cation Channels / metabolism*

Substances

  • N-(1-((4-(2-(((2,4-dichlorophenyl)sulfonyl)amino)-3-hydroxypropanoyl)-1-piperazinyl)carbonyl)-3-methylbutyl)-1-benzothiophene-2-carboxamide
  • Sulfonamides
  • TRPV Cation Channels
  • TRPV4 protein, human
  • Leucine