Stepping Up Human Beige Fat Cell Production

Wenli Yang; Patrick Seale

doi:10.1016/j.celrep.2018.11.091

Stepping Up Human Beige Fat Cell Production

Cell Rep. 2018 Dec 11;25(11):2935-2936. doi: 10.1016/j.celrep.2018.11.091.

Authors

Wenli Yang¹, Patrick Seale²

Affiliations

¹ Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: [email protected].
² Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: [email protected].

PMID: 30540928
DOI: 10.1016/j.celrep.2018.11.091

Abstract

Beige fat cells hold significant promise for reducing obesity and metabolic disease. Su et al. (2018) present a robust method to produce human beige adipocytes from pluripotent stem cells via the generation of an expandable intermediary population of mesenchymal progenitor cells.

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MeSH terms

Adipocytes, Beige*
Cell Cycle
Humans
Megakaryocyte-Erythroid Progenitor Cells
Mesenchymal Stem Cells*
Obesity