Since the end of last century direct electric brain stimulations have produced remarkable neurophysiological results. Unfortunately, this method can be used only during neurosurgical operations. With the introduction of transcranial electric brain stimulation in 1980, for the first time, it became possible to perform brain stimulations on non-anaesthetized subjects. Magnetic brain stimulation, available since 1985, allows brain stimulation without any discomfort of the subject. This paper is dealing with methodological aspects of both methods and presents first results of neurophysiological and clinical applications.