Abstract
This retrospective study investigated the possible adverse effects of cancer therapy on the brain. Cranial computed tomographic scans of 76 patients with non-central nervous system malignancies and 25 patients with leukemia had enlarged lateral ventricles and/or cortical sulci in 19% and 40%, respectively. Leukemic patients, especially those with meningeal involvement, had the most frequent and most severe abnormalities.
MeSH terms
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Adolescent
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Adult
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Antineoplastic Agents / adverse effects*
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Central Nervous System Diseases / chemically induced
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Central Nervous System Diseases / diagnostic imaging
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Central Nervous System Diseases / pathology
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Cerebral Ventricles* / pathology
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Cerebral Ventriculography
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Child
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Child, Preschool
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Female
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Humans
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Infant
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Leukemia / drug therapy*
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Leukemia, Lymphoid / drug therapy
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Leukemia, Myeloid / drug therapy
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Retrospective Studies
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Subarachnoid Space* / diagnostic imaging
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Subarachnoid Space* / pathology
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Tomography, X-Ray Computed